Home BLAST Help About  

otx2 (Homeobox Protein otx2)

Organism
Danio rerio (Zebrafish)
Phylogeny
Genomic Map Locations
otx2-b
Dr_Chr.17
Paralogs
Sequencing Methods
otx2-b: Sanger sequencing
Citations
  • Schaffer AE., Eggens VR., Caglayan AO., Reuter MS., Scott E., Coufal NG., Silhavy JL., Xue Y., Kayserili H., Yasuno K., Rosti RO., Abdellateef M., Caglar C., Kasher PR., Cazemier JL., Weterman MA., Cantagrel V., Cai N., Zweier C., Altunoglu U., Satkin NB., Aktar F., Tuysuz B., Yalcinkaya C., Caksen H., Bilguvar K., Fu XD., Trotta CR., Gabriel S., Reis A., Gunel M., Baas F, Gleeson JG. (2014). CLP1 founder mutation links tRNA splicing and maturation to cerebellar development and neurodegeneration. Cell 157(3):651-663. doi:10.1016/j.cell.2014.03.049.
  • Heather D. Veilleux, Lynne Van Herwerden, Nicholas J. Cole, Emily K. Don, Christian De Santis, Danielle L. Dixson, Amelia S. Wenger, Philip L. Munday. (2013). Biology Open 2:907-915. doi:10.1242/​bio.20135496.
  • Samarut E., Gaudin C., Hughes S., Gillet B., de Bernard S., Jouve PE., Buffat L., Allot A., Lecompte O., Berekelya L., Rochette-Egly C., Laudet V. (2014). Retinoic acid receptor subtype-specific transcriptotypes in the early zebrafish embryo. Molecular Endocrinology 28(2):260-272. doi:http://dx.doi.org/10.1210/me.2013-1358
  • Luz M., Spannl-Muller S., Ozhan G., Kagermeier-Schenk B., Rhinn M., Weidinger G., Brand M. (2014). Dynamic association with donor cell filopodia and lipid-modification are essential features of Wnt8a during patterning of the zebrafish neuroectoderm. PLoS ONE 9(1):E84922. doi:10.1371/journal.pone.0084922.
  • Chatterjee M., Guo Q., Weber S., Scholpp S., Li JY. (2014). Pax6 regulates the formation of the habenular nuclei by controlling the temporospatial expression of Shh in the diencephalon in vertebrates. BMC Biology 12:13. doi:10.1186/1741-7007-12-13.
  • Kapp LD., Abrams EW., Marlow FL., Mullins MC. (2013). The integrator complex subunit 6 (Ints6) confines the dorsal organizer in vertebrate embryogenesis. PLoS Genetics. 9(10):E1003822. doi: 10.1371/journal.pgen.1003822
  • Kobayashi M., Toyama R., Takeda H., Dawid IB., Kawakami K. (1998). Overexpression of the forebrain-specific homeobox gene six3 induces rostral forebrain enlargement in zebrafish. Development 125(15):2973-2982
  • Koshida S., Shinya M., Mizuno T., Kuroiwa A., Takeda H. (1998). Initial anteroposterior pattern of the zebrafish central nervous system is determined by differential competence of the epiblast. Development 125(10):1957-1966.
  • Fisher S., Amacher SL., Halpern ME. (1997). Loss of cerebum function ventralizes the zebrafish embryo. Development 124(7):1301-1311.
  • Hammerschmidt M., Bitgood MJ., McMahon AP. (1996). Protein kinase A is a common negative regulator of Hedgehog signaling in the vertebrate embryo. Genes & Development 10(6):647-658. doi:10.1101/gad.10.6.647._ANNOTATE_SEPERATOR2 Li Y., Allende ML., Finkelstein R., Weinberg ES. (1994). Expression of two zebrafish orthodenticle-related genes in the embryonic brain. Mechanisms of Development 48(3):229-244. doi: 10.1016/0925-4773(94)90062-0.
  • Gamse JT., Shen YC., Thisse C., Thisse B., Raymond PA., Halpern ME., Liang JO. (2002). Otx5 regulates genes that show circadian expression in the zebrafish pineal complex. Nature Genetics 30(1):117-121. doi:10.1038/ng793.
  • Veilleux HD., Van Herwerden L., Cole NJ., Don EK., De Santis C., Dixson DL., Wenger AS., Munday PL. Otx2 expression and implications for olfactory imprinting in the anemonefish, Amphiprion percula. Biology Open 2(9):907-15. doi:10.1242/bio.20135496.
  • fish-it.org.
    		•
    Sequence >NM_131251.1 Danio rerio Homeobox Protein otx2-b
    TCATTTGCTTCACGGTTTGAAGAAAAGGATATTATCCTGATGTTATGAATATTTTTCTAATAATTTAGAGCTGTATTCGC
    TATCGGACATCAAACTTTAACGGGCATCGGCTTGAATCCAGTTATTCAGGTTTTTAGTTTTACCTCCACCGCTGAAGACG
    CAAACAAGCTAAAGCAGAAGTGCGCTAAGGAAAAGAGACCGAAGCAGCCGGTTTCCAGTTTTCCGAAATTTCTCCAACTT
    TACCCCCCACAACCATCTTTAGCATGATGTCGTATCTCAAGCAACCACCTTACACGGTCAACGGGCTAAGTTTAACTACC
    TCCGGGATGGATCTTCTGCACCCCTCCGTTGGATACCCAGCGACTCCTCGAAAGCAGAGACGAGAAAGGACAACATTTAC
    TAGAGCGCAACTAGATGTGCTGGAGGCTTTATTCGCGAAAACACGCTACCCGGATATTTTCATGCGCGAGGAGGTGGCCT
    TGAAAATCAACTTGCCGGAGTCCCGTGTACAGGTTTGGTTCAAAAACCGAAGGGCAAAGTGTCGCCAACAGCAGCAACAA
    CAACAAAACGGAGGCCAGAACAAGGTGCGACCTGCCAAAAAGAAGAGCTCTCCAGCGCGGGAGGCCAGTTCTGAGAGCGG
    GGCGAGTGGCCAGTTCACCCCGCCCTCCAGTACTTCAGTCCCGGCCATCTCTACCACAACCGCTCCGGTGTCTATTTGGA
    GCCCAGCCTCTATCTCGCCGCTGTCAGACCCACTTTCTACCTCCTCCTCCTGCATGCAAAGATCCTACCCCATGACCTAC
    ACTCAAGCGTCTGGATATAGCCAGGGCTATGCTGGTTCCACTTCCTACTTTGGGGGTATGGACTGCGGCTCATACTTGAC
    GCCCATGCACCATCAGCTGACCGGGCCGGGATCCACTTTGAGCCCCATGAGCAGCAACGCTGTCACCAGTCACCTAAATC
    AGTCCCCCGCGTCCCTCCCCACACAAGGTTACGGTGCCTCGGGGCTCGGCTTCAACTCCACCGCGGATTGCTTGGATTAT
    AAGGACCAAGCGTCCTCATGGAAACTGAACTTCAATGCTGACTGCTTGGATTACAAAGATCAGACTTCCTCCTGGAAATT
    CCAAGTGTTGTGAAACTAAAAACCATCTACCACTCTGTCCAACCAACACCCTAAAAGACCATAAAATAAACGTTGTAGAC
    CTGCCATCCTTCCAATAACAGAAGTGTTCCGTGACGCGCGAACTCTCCCAGATGGATGGGTTGCATTAAGCCCAAGAGCG
    CTTGTGAAGTTTGAAGTCTTTGACATGAAATATCTATGTGAGCTACACGCAACCCTTGCTGGCGTGCAGAGTAGTTTTTG
    AAGGGTCGTGAATGCGTATAAACATAGGCCATTTGACCACAACCTGTTGTTAAAGGTGCAGGGAGTCAAAGTGAATTTGT
    AATAAGTTAGGTCAAAGCCACGGAACAAATCCTTACACAAGAAAAGAGGAGAAAAAACTACACAGCAAAAGGAGCCAATC
    TTTTGGTTAAGTGCTTGGAATGGGCAGGCTTTCTCTAAGCCTCTTACAGAACGCCGACCTATTTCAATGTTGGCAAGACG
    AGAGACACTTCCATCAGGAGGATGATAGAGAGGATGTGTGCGAGTGTACGTGTGTGCGTGCGTGTGTGTGTGCTGAACGC
    CCCCATGGCGACCTGGATGCACTACTTTATTTAAGAAAAGGTGTTTATAAGGAATCAATATGTAGTTTTTAAAGACAATC
    AATGTGTGTCTTATATAAATGGTACATTTGTGTTTTTTATCTGTGCTAGCCCTCGAAACTGTGATCTGTTGTAACTGTAT
    GCAATTTGTGAGCTCCGCCGCATCTGCGAAGACTCGGCTGTGATTTTAATAGATTTTAAACTTTTTTTTTTGGTTTGGAT
    TTGTTTAAGAAAACACGACAGTAAATAATACTAGTCATATGATTGCTATTGGATTAATTTCAAGAGACAAACTATCTCGG
    AAACACAGGGACTCAAGAGAATGTGTAAGAAAGGAACTGTCTGTCCCCGTTCATTGATCTTCATTGGTCATAACTGCTAT
    ACCACCCACGTGGATCTTAAACTTGTCTGGAGCGGTAATGTGGTCCCGCCACAGAAATATTAATAAACAATTTCAAATCT
    G
    Send to
    		or



    Organism

    GO term(s)

    Gene Expression

    Gene Structure

    Possible Primers

    Phylogeny (Gene Tree)

    Synteny

    Genomic Map Locations

    Paralogs

    Sequencing Methods

    Citations

    Sequence

    Gene Domains

    Molecular Markers


    Data input by M.Iliopoulou E.Sarropoulou
    CLICK IMAGES
    FOR LARGER SIZE