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GAPDH (Glyceraldehyde-3-phospate dehydrogenase)

Organism
Danio rerio (Zebrafish)
GO term(s)
Molecular Function: GO:0004365
Cellular Component: GO:0097452
Gene Expression 
UNIGENE: Approximate expression patterns inferred from EST sources. EST profiles show approximate gene expression patterns as inferred from EST counts and the cDNA library sources (as reported by sequence submitters). Libraries known to be normalized, subtracted, or otherwise biased have been removed, but for a variety of reasons, EST counts may not be a true indication of gene activity.GAPDH-1: Visit UniGeneGAPDH-2 (GAPDHS): Visit UniGene

GAPDH-1

Breakdown by Body Sites



Breakdown by Developmental Stage


GAPDH-2

Breakdown by Body Sites



Breakdown by Developmental Stage
Gene Structure


Phylogeny
Genomic Map Locations
GAPDH-1
Visit Map Viewer

GAPDH-2
CHR16: Visit Map Viewer
Paralogs
Sequencing Methods
GAPDH-1: Sanger sequencing

GAPDH-2 : Not available
Citations
  • Sarropoulou, E., Nousdili, D., Kotoulas, G. & Magoulas, A. (2011). Functional Divergences of GAPDH Isoforms During Early Development in Two Perciform Fish Species. Marine Biotechnology. doi: 10.1007/s10126-011-9375-6
  • McCurley AT., Callard GV. (2008). Characterization of housekeeping genes in zebrafish: male-female differences and effects of tissue type, developmental stage and chemical treatment. BMC Molecular Biology 9:102. doi: 10.1186/1471-2199-9-102.
  • Tang R., Dodd A., Lai D., McNabb WC., Love DR. (2007). Validation of zebrafish (Danio rerio) reference genes for quantitative real-time RT-PCR normalization. Acta Biochimica et Biophysica Sinica 39 (5):384-90. doi: 10.1111/j.1745-7270.2007.00283.x
  • Pei DS., Sun YH., Chen SP., Wang YP., Hu W., Zhu ZY. Zebrafish GAPDH can be used as a reference gene for expression analysis in cross-subfamily cloned embryos. (2007). Analytical Biochemistry 363(2):291-3. doi:10.1016/j.ab.2006.12.005.
  • Liu YJ., Zheng D., Balasubramanian S., Carriero N., Khurana E., Robilotto R., Gerstein MB. (2009). Comprehensive analysis of the pseudogenes of glycolytic enzymes in vertebrates: the anomalously high number of GAPDH pseudogenes highlights a recent burst of retrotrans-positional activity. BMC Genomics 10:480. doi: 10.1186/1471-2164-10-480.
  • Li X., Wu H., Zhang M., Liang S., Xiao J., Wang Q., Liu Q., Zhang Y. Secreted glyceraldehyde-3-phosphate dehydrogenase as a broad spectrum vaccine candidate against microbial infection in aquaculture. (2011). Letters in Applied Microbiology 54(1):1-9. doi: 10.1111/j.1472-765X.2011.03164.x.
  • Zheng Y., Xiao Y., Wu H., Wang Q., Xiao J., Zhang Y., Liu Q. Different approaches to expressing Edwardsiella tarda antigen GAPDH in attenuated Vibrio anguillarum for multivalent fish vaccines. (2012). Journal of Fish Diseases 35(8):569-77. doi: 10.1111/j.1365-2761.2012.01381.x.
  • Liang S., Wu H., Liu B., Xiao J., Wang Q., Zhang Y. (2012). Immune response of turbot (Scophthalmus maximus L.) to a broad spectrum vaccine candidate, recombinant glyceraldehyde-3-phosphate dehydrogenase of Edwardsiella tarda. Veterinary Immunology and Immunopathology 150(3-4):198-205. doi: 10.1016/j.vetimm.2012.09.036.
  • Strausberg RL., Feingold EA., Grouse LH., Derge JG., Klausner RD, Collins FS., Wagner L., Shenmen CM., Schuler GD., Altschul SF., Zeeberg B., Buetow KH., Schaefer CF.,Bhat NK., Hopkins RF., Jordan H., Moore T., Max SI., Wang J., Hsieh F., Diatchenko L.,Marusina K., Farmer AA., Rubin GM., Hong L., Stapleton M., Soares MB., Bonaldo MF., Casavant TL., Scheetz TE., Brownstein MJ., Usdin TB., Toshiyuki S., Carninci P., Prange C., Raha SS., Loquellano NA., Peters GJ., Abramson RD., Mullahy SJ., Bosak SA., McEwanPJ., McKernan KJ., Malek JA., Gunaratne PH., Richards S., Worley KC., Hale S., Garcia AM., Gay LJ., Hulyk SW., Villalon DK., Muzny DM., Sodergren EJ., Lu X., Gibbs RA., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madan A.,Young AC., Shevchenko Y., Bouffard GG., Blakesley RW., Touchman JW., Green ED., Dickson MC., Rodriguez AC., Grimwood J., Schmutz J., Myers RM., Butterfield YS., Krzywinski MI., Skalska U., Smailus DE., Schnerch A., Schein JE., Jones SJ., Marra MA. (2002). Mammalian Gene Collection Program Team. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences 99(26):16899-903. doi: 10.1073/pnas.242603899
  • Rodríguez-Aznar E., Nieto MA. (2011). Repression of Puma by Scratch2 is required for neuronal survival during embryonic development Cell Death Differ 18(7): 1196–1207. doi:10.1038/cdd.2010.190
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    Sequence >BC115131 Danio rerio Glyceraldehyde-3-phospate dehydrogenase-1
    CCACACTCACACCAAGTGTCAGGACGAACAGAGGCTTCTCACAAACGAGGACACAACCAAATCAGGCATAATGGTTAAAG
    TTGGTATTAACGGATTCGGTCGCATTGGCCGTCTGGTGACCCGTGCTGCTTTCTTGACCAAGAAAGTGGAGATCGTGGCC
    ATCAATGACCCATTCATTGACCTTGATTACATGGTTTACATGTTCCAGTACGACTCCACCCATGGAAAGTACAAGGGTGA
    GGTTAAGGCAGAAGGCGGCAAACTGGTCATTGATGGTCATGCAATCACAGTCTATAGCGAGAGGGACCCAGCCAACATTA
    AGTGGGGTGATGCAGGTGCTACTTATGTTGTGGAGTCTACTGGTGTCTTCACTACTATTGAGAAGGCTTCTGCTCACATT
    AAGGGTGGTGCAAAGAGAGTCATCATCTCTGCCCCAAGTGCAGATGCCCCCATGTTTGTCATGGGTGTCAACCATGAGAA
    ATATGACAACTCTCTCACAGTTGTAAGCAATGCCTCCTGCACCACCAACTGCCTGGCTCCTTTGGCAAAGGTCATCAATG
    ATAACTTTGTCATCGTTGAAGGTCTTATGAGCACTGTTCATGCCATCACAGCAACACAGAAGACCGTTGATGGGCCCTCT
    GGGAAGCTGTGGAGGGATGGCCGTGGTGCCAGTCAGAACATCATCCCAGCCTCCACTGAGGCTGCCAAGGCTGTAGGCAA
    AGTAATTCCTGAGCTCAATGGCAAGCTTACTGGTATGGCCTTCCGTGTCCCCACCCCCAATGTCTCTGTTGTGGATCTGA
    CAGTCCGTCTTGAGAAACCTGCCAAGTATGATGAGATCAAGAAAGTCGTCAAGGCTGCAGCTGATGGGCCCATGAAAGGA
    ATTCTGGGATACACGGAGCACCAGGTTGTGTCCACTGACTTCAATGGGGATTGCCGTTCATCCATCTTTGACGCTGGTGC
    TGGTATTGCTCTCAACGATCACTTTGTCAAGCTGGTCACATGGTATGACAATGAGTTCGGTCACAGCAACCGTGTATGTG
    ACCTGATGGCACACATGGCCTCCAAGGAGTAGATGTGACCCCTTTGCTGTTTCTTTTTTTTGATACGCGACCATTCTCCC
    ATCTGGTTGAATGTTTGCACCACGTGCCTGGAAGGAAATTACATGCTTAAATTGAAGACCAATATTATTTTTATATACTC
    TGTTCTGTTTCGTGTGTGAGGTTAAAAATAAATGTTGACTTCAAAGGCTTTTCTGTCTGTTAACAACTTGCGATGGAATA
    AAAGTCCTCTGTTTGTGAGAAATGGAAAAAAAAAAAAAAAAAAA
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    >AY818346 Danio rerio Glyceraldehyde-3-phospate dehydrogenase-2
    GGCGCACAATCCACACTCTTGCAATAATGTCTGAGCTTTGTGTTGGAATCAATGGATTTGGCCGTATTGGCCGTTTGGTC
    CTCAGGGCCTGCCTGCAGAAGGGAATTAAAGTCACCGCCATCAACGACCCCTTCATTGACCTGCAGTACATGGTCTACAT
    GTTCAAGTATGACTCCACTCATGGCCGTTACAAGGGAGAAGTTCACATGGAGGATGGAAAACTGATCGTTGATGGTCAGG
    CCATCTCTGTGTTCCAGTGCATGAAGCCTGCTGAGATCCCATGGGGGGATGCTGGTGCCCTGTACGTGGTCGAGTCCACC
    GGAGTCTTCCTCAGCATTGAGAAGGCCTCAGCTCACATCCAGGGTGGAGCCAAGCGTGTGGTTGTGTCTGCTCCATCACC
    CGACGCACCCATGTTTGTGATGGGAGTCAACCAGGACAAATATGACCCCTCCAGCATGACCATTGTCAGCAATGCATCCT
    GCACCACTAACTGCTTGGCTCCTCTGGCTAAAGTTATTCATGACAACTTTGGTATTGAGGAGGCTCTCATGACCACAGTT
    CATGCCTACACCGCCACACAGAAGACTGTCGATGGCCCCTCTGCCAAGGCATGGCGTGATGGACGTGGCGCCCACCAGAA
    CATCATCCCTGCATCCACTGGTGCCGCCAAGGCTGTGGGCAAAGTCATTCCTGAGCTTAACGGAAAGCTGACTGGTATGG
    CTTTCCGTGTGCCAGTCGCTGATGTGTCCGTTGTCGACCTCACCTGCCGCCTTACAAGGCCCGCCAGCTACGCCAACATC
    AAGGAGTCTGTCAAGAAGGCCGCTCATGGGCCAATGAAGGGAATTCTGGGATACACAGAGGATTCAGTCGTTTCTTCTGA
    CTTTGTTGGAGACACTCACTCTTCAATCTTTGATGCCGGCGCTGGCATCTCCCTCAATGACAACTTTGTCAAGCTCATCT
    CCTGGTATGACAACGAATTTGGCTACAGCCATCGTGTTGCTGACCTGTTAATGTACATGCACTCCAAAGAGTAACTCCGC
    AGAAAAGCCAGACCATTCCTTCTTTTCAACGCACTCATTTCCTAGCTAAAGCCATCGTGACACACCTTAGCATTCCTGTT
    CCCACCTACGAGACGCTGCGTTCGTCTCTGTAGATGTCTGTGTGTGTGTGTTAGTTTCTTTTGACAGTATTTGTGTCAGT
    GTCACTCCACAGGCATTGCTGTAGTTGTTGCCATTTTGGGTGTAATCACGTTGTGTTGGTGTAAAGAGAATAACCGAATA
    AAGTTACATGAGGTATAAAGGCTACTGTAATGCAGTTTAAAAAAACTAATTAAACTGTTTGGAAAAACAAAAAAAAAAAA
    AAAA
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    Organism

    GO term(s)

    Gene Expression

    Gene Structure

    Possible Primers

    Phylogeny (Gene Tree)

    Synteny

    Genomic Map Locations

    Paralogs

    Sequencing Methods

    Citations

    Sequence

    Gene Domains

    Molecular Markers


    Data input by E.Sarropoulou
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